The frown is located between the eyebrows. A frown wrinkle can occur due to the repeated tightening of the frown muscle. This can sometimes give an angry or stern appearance. With a treatment of a wrinkle relaxant (botulinum toxin), the frown muscle can become so relaxed that temporarily there will be less frowning. This makes the lines softer and the appearance is also more relaxed and friendly. Often the frown is treated in combination with the forehead.